I have only had epson printers, (although I'm only on my second one, and epson gave that to me for free

) Anyway I haven't used anything besides Epson ink, but a friend of mine did and it ruined his printer. The technology that Epson uses is different than most and if you use generic ink it can clog up the printer.
I would recommend finding a good deal on the ink rather than buying generic...just my $.02